We propose a model mechanism for the initiation and spatial positioning of teeth primordia in the alligator, Alligator mississippiensis. Detailed embryological studies by Westergaard and Ferguson have shown that jaw growth plays a crucial role in the developmental patterning of the tooth initiation process. Based on biological data we develop a dynamic patterning mechanism, which crucially includes domain growth. The mechanism can reproduce the spatial pattern development of the first seven teeth primordia in each half jaw of A. mississippiensis. (...) The results for the precise spatio-temporal sequence compare well with experiment. Simulation of the model also predicts that certain transplantations can alter the spatial sequence of teeth primordia initiation. (shrink)

Background: According to the Declaration of Helsinki, patients who take part in a clinical trial must be adequately informed about the trial's aims, methods, expected benefits, and potential risks. The declaration does not, however, elaborate on what “adequately informed” might amount to, in practice. Medical researchers and Local Research Ethics Committees attempt to ensure that the information which potential participants are given is pitched at an appropriate level, but few studies have considered whether the patients who take part in such (...) trials feel they have been given adequate information, or whether they feel able to understand that information.Objectives: To explore trial participants' views on the amount of information provided, and of their own understanding of that information.Design: Structured interviews of patients participating in clinical trials for the treatment of chronic medical condition.Findings: Patients generally felt they were given an appropriate amount of information, and that they were able to understand all or most of it. They felt they were given adequate time to ask questions before agreeing to take part. In comparison with treatment given outwith the research setting, patients generally felt they received more information when participating in a clinical trial.Conclusions: Researchers sometimes complain that patients are given too much information during clinical trials, and have limited understanding of that information. The present study shows that this perception is not necessarily shared by patients. More research is needed in this area, particularly to gauge whether patient understanding is indeed accurate. (shrink)

Recent studies in social endocrinology have explored the effects of social relationships on female reproductive steroid hormones—estradiol and progesterone—investigating whether they are suppressed in partnered and parous women. Results have been mixed for these hormones although evidence is more consistent that partnered women and women with young children have lower levels of testosterone. These studies were sequential to earlier research on men, based on Wingfield’s Challenge Hypothesis, which showed that men in committed relationships, or with young children, have lower levels (...) of testosterone than unpartnered men or men with older or no children. The study described here explored associations between estradiol and progesterone with partnership and parity among women from two different ethnicities: South Asian and white British. We hypothesized that both steroid hormones would be lower among partnered and/or parous women with children ≤3 years old, regardless of ethnicity. In this study we analyzed data from 320 Bangladeshi and British women of European origin aged 18 to 50 who participated in two previous studies of reproductive ecology and health. Levels of estradiol and progesterone were assayed using saliva and/or serum samples and the body mass index calculated from anthropometric data. Questionnaires provided other covariates. Multiple linear regressions were used to analyze the data. The hypotheses were not supported. We argue here that, unlike links between testosterone and male social relationships, theoretical foundations for such relationships with female reproductive steroid hormones are lacking, especially given the primary role of these steroids in regulating female reproductive function. Further longitudinal studies are needed to explore the bases of independent relationships between social factors and female reproductive steroid hormones. (shrink)

This study statistically analyzes two-year college students' attitudes toward cheating via a survey containing academic and business situations that the students evaluated on a seven point scale from unethical to ethical. When both the general questions concerning attitudes about cheating and the opinions on the ethical statements are considered, the business students were generally more unethical in their behavior and attitudes than non-business majors. These results indicate a need for more ethical exposure in business courses to help students distinguish ethical (...) from unethical decisions. (shrink)

The 2011 Historical Materialism Conference in London saw the launch of a Marxist-Feminist set of panels. This issue is inspired by the success of those panels, and the remarkably sustained interest in reviving and moving beyond older debates and discussions. The special issue’s focus, Social-Reproduction Feminism, reflects and contextualises the ongoing work and engagement with that thematic that has threaded through the conferences in the 2010s. This Introduction provides a summary overview of the Social-Reproduction Feminism framework, situating it within Marxist-Feminist (...) thinking and politics more generally, and calls on readers to consider its promise and potential as an historical-materialist approach to understanding capitalist social relations in terms of an integrated totality. (shrink)

Several cases which have been considered by the courts in recent years have highlighted the legal dilemmas facing doctors whose decisions result in the ending of a patient's life. This paper considers the case of Dr Cox, who was convicted of attempting to murder one of his patients, and explores the roles of motive, diminished responsibility and consent in cases of "mercy killing". The Cox decision is compared to that of Tony Bland and Janet Johnstone, in which the patients were (...) in a persistent vegetative state. In all three cases, the doctors believed that their patients' quality of life was so poor that their continued existence was of no benefit to them, and decided that their lives should not be unduly prolonged, yet the doctor who was prosecuted was the one whose dying patient had requested that her death be hastened. The paper examines the law's seemingly contradictory approaches to such cases. (shrink)

It is both an ethical and a legal requirement that patients who participate in clinical trials must generally give their consent. As part of this process, patients must be provided with adequate information to enable them to decide whether or not to take part. In the UK, the pharmaceutical companies that sponsor such research, as well as Local Research Ethics Committees, specify in detail the information that must be given to trial participants. The researchers who conduct clinical trials inevitably form (...) views on the amount of information they are required to provide, and about patients’ comprehension of that information. The literature in this area suggests that some medical researchers may be unhappy with the amount of information that they must give patient participants. There have been, however, few systematic attempts to determine their views. This paper reports a study that explored researchers’ views as to (i) the amount of information provided to trial participants, and (ii) participants’ understanding of that information. Researchers generally felt that they were required to give trial participants an appropriate amount of information, and that most patients had at least a reasonable understanding of key aspects of the clinical trials’ process. However, there were differing views as to the level of information that they felt patients themselves wanted. The researchers did not generally feel that the patients’ inability to comprehend information rendered the process of obtaining ‘informed consent’ a waste of time. However, some did believe that they were required to burden patients with excessive information. (shrink)

An extensive body of Chinese philosophical thought suggests a redefinition of international security in terms of a non-threatening formulation of Comprehensive Security. In one culture viewed as particularly 'strategic', i.e. Chinese culture, we find strong traditions of inclusive, non-aggressive forms of security. Mo Tzu and the school of Mohism (5th-3rd centuries BC) developed a rigorous body of thought and practice based on universal regard, the protection of small states, and disesteem for aggressive wars. This is paralleled by a more general (...) emphasis in the classical Chinese philosophical and political tradition on the means of civilisation (wen) over the methods of brute warfare (wu). In modem regional crises such as the dispute between Taiwan and the PRC (People's Republic of China), it is crucial to engage the wen (cultured) aspect of the political tradition. In this context, deterrence of aggression by reciprocal threats is only a short-term solution. (shrink)

This book examines the politics, philosophy, and history of Chinese power, focusing on social, strategic, and diplomatic trends that have shaped China for over three thousand years. By probing political and philosophical trends, it provides an alternative analysis for the rise of contemporary China.

We examine deceptive impression management's effect on a supervisor's ratings of promotability and relationship quality (i.e., leader-member exchange) via the mediating role of the supervisor's recognition of deception. Extending ego depletion theory using social information processing theory, we argue that deceptive impression management in a supervisor-subordinate relationship is difficult to accomplish and the degree that deception is detected will negatively impact desired outcomes. Data collected from a matched sample of 171 public sector employees and their supervisors supported this model and (...) indicated that recognition fully mediated the negative relationships between deceptive impression management with supervisor's rating of promotability and relationship quality. (shrink)

This collection of original essays presents diverse perspectives on the hybrid, evolving traditions of Confucianism. The chapters explore contemporary harmony across philosophy, religion, politics, linguistics, diplomacy, international relations, and education, with writers from numerous cultural and national backgrounds.

We examine the relationship between the logics of nonsense of Bochvar and Halldén and the containment logics in the neighborhood of William Parry’s A I. We detail two strategies for manufacturing containment logics from nonsense logics—taking either connexive and paraconsistent fragments of such systems—and show how systems determined by these techniques have appeared as Frederick Johnson’s R C and Carlos Oller’s A L. In particular, we prove that Johnson’s system is precisely the intersection of Bochvar’s B 3 and Graham Priest’s (...) non-symmetrized connexive logic and that Oller’s system lies just beneath the intersection of B 3 and Priest’s paraconsistent L P. We conclude by examining Oller’s system in more depth, giving it a characterization in terms of L P and showing that it plays the same role to Harry Deutsch’s paraconsistent containment logic S that Aleksandr Zinov'ev’s S 1 plays with respect to A I. (shrink)

Meyer and Mortensen’s Alien Intruder Theorem includes the extraor- dinary observation that the rationals can be extended to a model of the relevant arithmetic R♯, thereby serving as integers themselves. Al- though the mysteriousness of this observation is acknowledged, little is done to explain why such rationals-as-integers exist or how they operate. In this paper, we show that Meyer and Mortensen’s models can be identified with a class of ultraproducts of finite models of R♯, providing insights into some of the (...) more mysterious phenomena of the rational models. (shrink)

This is a bibliography of R.K. Meyer's published articles on relevant arithmetic.

The Militant Listener: Reading Mongane Wally Serote's Sikhahlel' u-OR alongside Walter Benjamin's Theses on the Philosophy of History In Sikhahlel' u-OR: A Praise Poem for Oliver Tambo, Mongane Wally Serote presents an unflinching yet delicate meandering through the questions, reflections and provocations resistance history offers up through O. R. Tambo's life. As Ciraj Rassool points out, in this work Tambo appears not as an individual, but as an integral node in a web connecting various lives.1 This counter-neoliberal interpretation of Tambo's (...) life offers what Michael Löwy calls 'a heterodox form of the narrative of emancipation' rebuilding the struggle hero narrative along a decentred framework.2 By radically dislodging this narrative, Tambo is portrayed as the 'non-iconic icon' he was esteemed to embody, and in this move, the poem, notably, points to the dearth of dialectic politics, both in our quotidian praxis, and the commemoration of others.3 Aptly, Serote's work contributes to what Souleymane Bachir Diagne and Jean-Loup Amselle describe as a 'total decentring of all thought, one that rejects all "centrisms" and highlights instead branchings and connections, transfers, analogies and reciprocal influences between cultural places and intellectual fields that may be distant but are not distinct in space and time'.4 To this end, the poem presents us with a constellation of historical actors who flicker on the horizon, beckoning us to engage in the labour of freedom. (shrink)

This study examines the leading early nineteenth-century Scottish moral philosopher Dugald Stewart’s discussion of the origin and development of religion. Stewart developed his account in his final work, The Philosophy of the Active and Moral Powers of Man (1828), in an effort to show that the fact that polytheism was the first religion of humankind does not undermine the truth of monotheism. He wrote in response to similar discussions presented in David Hume’s “Natural History of Religion” (1757), which argued for (...) the primacy of polytheism, and Stewart’s old moral philosophy tutor Adam Ferguson’s Principles of Moral and Political Science (1792), which argued for the primacy of monotheism. Stewart accepted the conclusions of the Scots’ enlightened study of religion, which argued for truth of Hume’s account, but aimed to reassert many of the natural theological arguments about the naturalness of religion that the “Natural History” had challenged. Stewart’s discussion acts as a useful way by which we can assess the achievement of the literati’s study of religion. (shrink)

Summary Five recently discovered letters written by James Ferguson, FRS (1710?1776) while he was on a lecture tour in 1771 add substantially to what was previously known about his activities at that time. Together with newspaper advertisements and other correspondence, they not only enable his itinerary to be reconstructed in also reveal some of his own thoughts at the time and the difficulties that he had to contend with. On this particular tour, Ferguson was away from his London (...) base for at least seven months, visiting Birmingham, Kidderminster, Worcester, Newcastle-under-Lyme, Cheadle (Staffs.), and Derby. During this period he delivered his course of 12 lectures on Experimental Philosophy at least eight times. Amongst the people that he met were Matthew Boulton, Josiah Wedgwood, and John Whitehurst, as well as the recipient of the letters, James Beresford of Bewdley, Worcestershire. In this paper the opportunity has been taken to present also an outline of the gradual evolution of Ferguson's lecturing career, leading up to his situation in the 1770s, as much of the relevant source material now available was unknown to his nineteenth-century biographer, Ebenezer Henderson. (shrink)

The old question whether or no the doctrine of ‘intermediate mathematical objects’ ascribed to Plato by Aristotle is to be found in the Divided Line of Republic vi, has been recently raised again in a careful and lucid discussion by Mr. W. F. R. Hardie. I may clear the ground by saying at once that I agree with that part of Mr. Hardie's chapter which deals with those criticisms of the traditional view that have been put forward by Prof. (...) class='Hi'>Ferguson and the late Prof. Stocks; nevertheless I do not believe that the objects of the third segment are intermediate between Forms and Sensibles: I propose to argue that they, like the objects of the highest segment, are Forms. (shrink)

The old question whether or no the doctrine of ‘intermediate mathematical objects’ ascribed to Plato by Aristotle is to be found in the Divided Line of Republic vi, has been recently raised again in a careful and lucid discussion by Mr. W. F. R. Hardie. I may clear the ground by saying at once that I agree with that part of Mr. Hardie's chapter which deals with those criticisms of the traditional view that have been put forward by Prof. (...) class='Hi'>Ferguson and the late Prof. Stocks; nevertheless I do not believe that the objects of the third segment are intermediate between Forms and Sensibles: I propose to argue that they, like the objects of the highest segment, are Forms. (shrink)

Why Christianity, with its conception of agapé was successful in winning the allegiance of the late Romans is the question which leads Ferguson to his examination of the Homeric virtues and the Stoic morality. He finds the classical virtues are incapable of "providing that basis for an universal morality for which people were seeking" because they were each linked to a vanished society or failed to reach to the heart of men's moral strivings. His analysis of the pagan virtues (...) is less than sympathetic, though thoughtful and based on considerable learning.--R. F. T. (shrink)